Hi guys, this is my first post. I'm a 43 year old female with anxiety/IBS-D which I have had for as long as I can remember. I've recently come off escitalopram (was on it for 6 years) due to a doctor not giving me a repeat prescription as I am also on hydroxychloroquine and she was concerned about interactions. She has talked me into changing to sertraline which I'm due to start in a few weeks. Whenever you look online it says SSRI's are mainly for IBS-C as they can cause diarrhoea. My question is has anyone had any better results with certain anti depressants for IBS-D? Note I also use codeine to manage symptoms at times of high anxiety/stressful situations.