IBS-M: diarrhea in the morning and constipation at night?

That sounds really hard, I'm sorry. Have you tried changing your diet to see if that does anything? I usually find that I feel better in the morning if I don't eat late at night. For me personally, eating breakfast also helps me go to bathroom in the evenings rather than in the mornings. Since you mention that you also have anxiety, there might be a link between that and the symptoms you have in the morning: https://irritablebowelsyndrome.net/living/morning-anxiety, https://irritablebowelsyndrome.net/living/why-ibs-symptoms-worse-morning. Maybe doing something that reduces stress first thing in the morning might help? Wishing you all the best, Karina (team member)