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Symptoms Of IBS: Non-Gastrointestinal Symptoms

The most common non-gastrointestinal symptoms may be chronic fatigue syndrome, temporomandibular joint disorder (TMJ), and fibromyalgia.

What is chronic fatigue syndrome?

Chronic fatigue is described as a permanent and intense fatigue of unknown cause that limits a person’s ability to function. These symptoms persist for at least 6 months and do not improve with rest.1 IBS is present in 51% of people with chronic fatigue syndrome.2

What is TMJ?

TMJ includes symptoms related to pain of the temporomandibular joint and surrounding areas.1 The temporomandibular joint is like a hinge in the jaw area that lets you move your jaw in various motions for talking, chewing, and yawning. IBS is present in 64% of people with TMJ.2

What is fibromyalgia?

Fibromyalgia is a chronic and widespread pain that is typically associated with fatigue, anxiety, sleep disturbances, and loss of intellectual functions.1 Approximately 20%-50% of IBS patients have fibromyalgia.2

Other non-GI symptoms

Sleep disturbances were found in 28% to 74% of people with IBS. Other non-GI symptoms found among people with IBS include chronic pelvic pain and tension headaches.2,3

Written by: Truc Thanh | Last reviewed: June 2016.
  1. Kim SE, Chang L. Overlap between functional GI disorders and other functional syndromes: what are the underlying mechanisms? Neurogastroenterol Motil. 2012;24:895-913.
  2. World Gastroenterology Organisation Global Guidelines. Irritable Bowel Syndrome: a Global Perspective. Accessed 1/7/16 at:
  3. Hausteiner-Wiehle C, Henningsen P. Irritable bowel syndrome: relations with functional, mental, and somatoform disorders. World J Gastroenterol. 2014;20:6024-6030.