"Replying to lady who stated what she did for flares. It's hard for me to answer, because I've had constant worries about diarrhea for 50+ years. I always worried about it. If she is talking about pain, that I can answer. It usually comes on the night. I take an ibuprofen and Pepto Bismol, try to empty out as best I can, and go back to bed with a heating pad. Works like a charm."